Technical indicators of clean laboratory - biosafety laboratory: 1) The noise does not include the noise of biosafety cabinet and animal isolator. If the noise of the above equipment is included, the maximum shall not exceed 68dB(A). 2) The minimum negative pressure of the Level 3 biosafety main laboratory relative to the atmosphere shall not be less than -30Pa, and the minimum negative pressure of the Level 4 biosafety main laboratory relative to the atmosphere shall not be less than -50Pa. 3) The minimum negative pressure relative to the atmosphere of the Level 3 biosafety main laboratory for raising animals shall not be less than -50Pa, and the minimum negative pressure relative to the atmosphere of the Level 4 biosafety main laboratory for animals shall not be less than -60Pa. 4) Animal cleaning laboratory - the parameters of the biosafety laboratory should meet the relevant requirements of GB14925-2001 "Laboratory Animal Environment and Facilities".